Samsung, Celltrion Bet Big on $12.7 Billion Keytruda SC Market

■AI PRISM [Startup News] Samsung Bioepis Secures In-House SC Formulation Technology LG, GS to Jointly Develop Xi Complexes with AI Home, Robots Naver Recognized for LLM Safety Research at ICML 2026

Finance|
|
By Kang Do-won
||
null - Seoul Economic Daily Finance News from South Korea

▲AI PRISM* Customized Economic Briefing

*Editor's Note: 'AI PRISM' (Personalized Report & Insight Summarizing Media) is an "AI-based customized news recommendation and summary service" developed with support from the Korea Press Foundation. It selects and provides six customized news articles by reader type.

[Key Issue Briefing]

■ SC Formulation Competition: The global biosimilar industry is entering the competition over subcutaneous injection (SC) formulations. Samsung Bioepis has secured SC formulation technology in-house, meaning that following Celltrion (068270), both of Korea's two major biosimilar companies now have their own proprietary platforms. As a result, competition to preempt the market around the expiration timing of original drugs' substance patents is intensifying further.

■ AI Adoption Spreads: The adoption of artificial intelligence (AI) is rapidly spreading across Korean industry. LG Electronics (066570) has joined hands with GS Engineering & Construction (006360) to apply AI home and robot technology to its Xi apartments, while Samsung Electronics (005930) has introduced Google Cloud's "Gemini Enterprise" to employees worldwide, creating the largest-scale case in the Korean market. Meanwhile, Naver has demonstrated its AI technology competitiveness by earning recognition at a world-class academic conference for its research on detecting LLM vulnerabilities.

■ Glass Substrate Competition: Competition over next-generation semiconductor packaging materials is also gaining momentum in earnest. JNTC (204270) has signed a commercialization agreement with Japan's Toppan, leveraging its world-first through-glass via (TGV) glass substrate technology. As a result, cases of Korean materials companies entering the global supply chain are increasing.

[News of Interest to Startup Founders]

1. Two Years Until Keytruda Patent Expiry… Samsung Bioepis Targets '47 Trillion Won Market' with Proprietary Technology

- Key Summary: Samsung Bioepis has secured subcutaneous injection (SC) formulation technology in-house, expanding the global biosimilar competition into "formulation conversion." Merck's (MSD) Keytruda, which recorded $31.7 billion in revenue last year, is the world's top anticancer drug, and the SC formulation market alone amounts to $12.7 billion by simple calculation. Earlier, Celltrion also internalized PH20-based technology and has begun developing Herceptin SC and Darzalex SC biosimilars. Market research firm Mordor Intelligence forecast that the global SC biopharmaceutical market will grow from $286.3 billion this year to $498.9 billion in 2031.

2. Riding the Waves of Volatility, the Investor's Survival Equation

- Key Summary: There are concerns that single-stock leveraged exchange-traded funds (ETFs), listed in May this year, are structurally intensifying market volatility. The combined KOSPI market capitalization share of Samsung Electronics and SK hynix (000660) exceeds 50 percent, meaning that even investing in the benchmark index is effectively determined by the performance of these two stocks. As a result, investors must choose between a "head-on approach" that directly responds to volatility and a "wait-and-see" strategy that lowers risk. Both strategies were presented as options that vary depending on risk appetite, investment horizon, and the purpose of the funds.

3. LG-GS 'AI Robot' Alliance… Xi Apartments Get Smarter

- Key Summary: LG Electronics and GS Engineering & Construction signed a "Memorandum of Understanding for the Joint Development of Next-Generation AI Homes" and agreed to apply AI home and robot technology to the Xi apartment brand. LG Electronics' AI home platform "ThinQ On" links home appliances and Internet of Things (IoT) devices to automatically control ventilation, lighting, and heating, while also supporting elevator calls and parking location checks. Earlier, in April, the two companies signed a memorandum of understanding to build a future-oriented residential robot service model and established robot-friendly apartment design standards. Through this collaboration, LG Electronics has set a goal of securing a total of 4 million to 5 million households as customers, including 320,000 units in newly built apartments.

[Reference News for Startup Founders]

4. Finding and Optimizing LLM Vulnerabilities… Naver Proves 'AI Competitiveness'

- Key Summary: Team Naver's red-teaming research on detecting large language model (LLM) vulnerabilities was selected as a spotlight paper at the world-class machine learning conference "ICML 2026." Spotlight status is granted to only about 2.2 percent of all accepted papers, and Team Naver had a total of six papers accepted, including this research. "Stable GFlowNet," presented by Team Naver, is a technology that verifies attack vulnerabilities before an LLM is deployed in a service, and it was evaluated as having structurally resolved problems of learning instability and repetition of similar patterns. In addition, the model merging technique "Simerge" and the multi-agent collaboration technology "FlowBot" were also unveiled.

5. Samsung Electronics Adopts 'Gemini Enterprise'… "Utilizing Conversational Collaboration Space"

- Key Summary: Samsung Electronics has adopted Google Cloud's enterprise AI service "Gemini Enterprise," providing it to employees in its Device eXperience (DX) division worldwide. Google Cloud explained that this case is the largest-ever adoption of Gemini Enterprise agentic AI in the Korean market. Gemini Enterprise functions as a centralized gateway connecting scattered internal systems, and Samsung Electronics plans to introduce customized multi-step AI agents that autonomously manage complex workflows. Google Cloud plans to support not only development personnel but also non-development personnel in building AI agents through a no-code method.

6. JNTC Joins Hands with Japan's Toppan for TGV Glass Substrate Commercialization

- Key Summary: Advanced materials company JNTC has signed a commercialization agreement with Japanese semiconductor packaging company Toppan, leveraging its world-first through-glass via (TGV) glass substrate technology. The company earlier succeeded in developing high-difficulty TGV glass substrates spanning glass thicknesses from 0.3mmT to 2.0mmT, and its recently developed 2.0mmT new product has secured a mass-production yield of around 94 percent. It explained that it has completed vertical integration of the entire pre-production process just two years after officially entering the semiconductor glass substrate new business in 2024. Cho Nam-hyuk, CEO of JNTC, said the company is carrying out projects with global semiconductor companies aimed at mass production in 2027.

▶Go to article: Hormuz Blocked Again… Government "Secures Two Months of Crude Oil"

▶Go to article: Court "Korea Zinc's Restriction of Young Poong's Voting Rights at Extraordinary General Meeting Is Illegal"

null - Seoul Economic Daily Finance News from South Korea
null - Seoul Economic Daily Finance News from South Korea
null - Seoul Economic Daily Finance News from South Korea
null - Seoul Economic Daily Finance News from South Korea
null - Seoul Economic Daily Finance News from South Korea
null - Seoul Economic Daily Finance News from South Korea

Original reporting by Kang Do-won for Seoul Economic Daily.

AI-translated from Korean. Quotes from foreign sources are based on Korean-language reports and may not reflect exact original wording.

Watch · Seoul Economic Daily

More →
3:12

AI KEY

Preview
Korean Corporate Intelligence HubKOSPI · KOSDAQ · 12 sectors

A live, cap-weighted view of every KOSPI and KOSDAQ sector, with same-day Korean reporting distilled by company — built for foreign investors, correspondents and analysts who need to scan Korea before the next session.

Korea Company Atlas

Preview
Market Ontology · The Feedback LoopKFTC 2025 · 92 groups · 121,954 articles

An English ontology of the Korean market — how companies, the media, the government and the National Assembly move each other in a loop. Korea's named controlling persons and designated business groups are a mechanism, not a risk to be priced blind.

SIGNAL

Now live
English Edition · Capital MarketsM&A · IPO · PE · Fund Flows

SIGNAL English Edition is live — Korea's deal desk reporting in English. M&A, IPOs, private equity and fund flows, covered daily for global institutional investors. Browse free; subscriber-only scoops at the 50% intro rate.